Balance the small benefits and potential risks of carpal tunnel release surgery

Balance the small benefits and potential risks of carpal tunnel release surgery

Vanessa Jordan
PEARLS No.
738
Clinical question

How does carpal tunnel release compare with non-surgical treatment for carpal tunnel syndrome?

Bottom line

At long-term follow-up, surgery probably provides better clinical improvement compared with splinting and manual therapy, but the benefits of surgery in symptoms and hand function seem to be small compared with non-surgical treatment. The decision for a patient to opt for surgery should balance the small benefits and potential risks of surgery.

Patients with severe symptoms, a high preference for clinical improvement and reluctance to adhere to non-surgical options, and who do not consider potential surgical risks and morbidity a burden, may choose surgery.

Alternatively, those who have tolerable symptoms, have not tried non-surgical options and want to avoid surgery-related morbidity can start with non-surgical options and have surgery only if they fail to achieve a satisfactory symptom state with non-surgical options.

Caveat

Whether the risk of adverse effects differs between surgery and non-surgical treatments is unknown. The severity of adverse effects may differ between surgery and non-surgical options, with surgery potentially causing rare severe adverse effects, such as deep wound or systemic infection or nerve injury, which are not plausible risks in non-surgical care. This should be explained to people who consider opting for surgery.

Context

Carpal tunnel syndrome is a compression neuropathy of the median nerve at the wrist. Surgery is considered when symptoms persist despite the use of non-surgical treatments. It is unclear whether surgery produces a better outcome than non-surgical therapy.

Cochrane Systematic Review

Lusa V, et al. Surgical versus non-surgical treatment for carpal tunnel syndrome. Cochrane Database Syst Rev 2024;1:CD001552. This review contains 14 trials with a total of 1231 participants.