Respiratory physician Lutz Beckert considers chronic obstructive pulmonary disease management, including the prevention of COPD, the importance of smoking cessation and pulmonary rehabilitation, and the lifesaving potential of addressing treatable traits. He also discusses the logic of inhaler therapy, moving from single therapy to dual and triple therapy when indicated, as well as other aspects of management
Arthroscopic surgery probably not warranted for degenerative knee disease
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Arthroscopic surgery probably not warranted for degenerative knee disease
What are the benefits and harms of arthroscopic surgery, including debridement, partial meniscectomy or both, compared with placebo surgery or non‐surgical treatment in people with degenerative knee disease (osteoarthritis, degenerative meniscal tears or both)?
The findings of this review demonstrate that arthroscopic surgery for people with symptomatic degenerative knee disease (average age ranging from 46 to 65; 56% women), provides little or no clinically important benefit in pain or function, probably does not provide clinically important benefits in knee‐specific quality of life, and may not improve treatment success compared with placebo surgery. These results apply to people with knee osteoarthritis with or without meniscal tears, as well as people with meniscal tears alone.
Arthroscopic surgery may or may not increase serious and total adverse events compared with control. Serious adverse events include deep venous thrombosis, myocardial infarction, pulmonary embolism, infection and death, and are likely mostly attributable to the arthroscopic surgery. Arthroscopic surgery may lead to greater progression of knee osteoarthritis and may or may not slightly increase subsequent need for knee surgery (replacement or osteotomy).
Overall, the trials included participants and interventions that are largely reflective of clinical practice, indicating that the results of the review can be broadly applied to practice. For the primary outcomes of pain and knee function, the overall certainty of the evidence was high. The certainty of evidence for quality of life was moderate, and due to potential publication bias and low numbers of participants, the certainty of evidence for adverse event outcomes was rated as low.
Arthroscopic knee surgery remains a common treatment for symptomatic knee osteoarthritis, including for degenerative meniscal tears, despite guidelines strongly recommending against its use.
O’Connor D, et al. Arthroscopic surgery for degenerative knee disease (osteoarthritis including degenerative meniscal tears). Cochrane Database Syst Rev 2022;3:CD014328. This review contains 16 trials with a total of 2105 participants.