Exercise beneficial for chronic fatigue syndrome

Exercise beneficial for chronic fatigue syndrome

Brian McAvoy
PEARLS No.
465
Clinical question

How effective is exercise therapy for patients with chronic fatigue syndrome?

Bottom line

Patients with chronic fatigue syndrome (CFS) generally benefit and feel less fatigued following exercise therapy, and no evidence suggests exercise therapy worsens outcomes. A positive effect with respect to sleep, physical function and self-perceived general health was observed, but no conclusions for the outcomes of pain, quality of life, anxiety, depression, drop-out rate and health service resources used were possible. The effectiveness of exercise therapy, in which exercise increments were set between trainer and patient, seems greater than that of pacing, in which patients set their own exercise increments, but similar to that of cognitive behavioural therapy. Exercise therapy lasted 12–26 weeks, and was performed 3–5 times/week, with a target duration of 5–15 minutes/session.

Caveat

There were substantial differences in participant illness severity, as illustrated by the wide range in baseline physical functioning, depression comorbidity and illness duration. Reported results were obtained from participants who were able to participate in exercise, not from those too disabled to attend clinics.

Context

CFS is characterised by persistent, medically unexplained fatigue, as well as symptoms such as musculoskeletal pain, sleep disturbance, headache, and impaired concentration and short-term memory. CFS presents as a common, debilitating and serious health problem.

Cochrane Systematic Review

Larun L et al. Exercise therapy for chronic fatigue syndrome. Cochrane Reviews, 2015, Issue 2. Art. No.: CD003200.DOI: 10.1002/14651858. CD003200.pub3. This review contains 8 studies involving 1518 participants.

 

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