Respiratory physician Lutz Beckert considers chronic obstructive pulmonary disease management, including the prevention of COPD, the importance of smoking cessation and pulmonary rehabilitation, and the lifesaving potential of addressing treatable traits. He also discusses the logic of inhaler therapy, moving from single therapy to dual and triple therapy when indicated, as well as other aspects of management
Glucocorticoids effective for croup in children
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Glucocorticoids effective for croup in children
How effective are glucocorticoids for the treatment of croup in children aged up to 18 years?
Glucocorticoids improved croup symptoms at 2 hours (moderate‐certainty evidence), and the effect lasted at least 24 hours (low‐certainty evidence). Glucocorticoids reduced rates of return visits, hospital admissions and readmissions (moderate‐certainty evidence). Glucocorticoids reduced length of hospital stay by 15 hours (range 6 to 24 hours), but made no difference in need for additional treatments. There appeared to be no additional benefit from combined dexamethasone and budesonide in comparison with using either treatment alone. Few serious adverse events were reported related to short‐term treatment with glucocorticoids for croup.
It was not certain which type, amount and administration mode (oral, inhaled, injected) of glucocorticoids was best for reducing symptoms of croup in children.
Croup causes oedema of the throat and trachea, resulting in hoarseness, a barking cough and noisy breathing. Glucocorticoids can reduce swelling, making it easier to breathe.
Gates A et al. Glucocorticoids for croup in children. Cochrane Reviews, 2018, Issue 8. Art. No.: CD001955.DOI: 10.1002/14651858. CD001955.pub4. This review contains 43 studies involving 4565 participants.