Mean cell volume: Big is not better and should always be explained

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In print

FROM THE LAB

Mean cell volume: Big is not better and should always be explained

10 November 2021

By Ian Morison

Wednesday 10 November 2021, 12:40 AM

Like using lawn fertiliser to make a healthy lawn grow more vigorously, a high circulating iron level enhances haemoglobin synthesis [Image: Rémi Müller on Unsplash]

The most common causes of macrocytosis are probably excess alcohol consumption and liver disease, but this article also considers the less well recognised causes, including reticulocytosis, myelodysplastic syndrome, myeloma and others

Key points, Macrocytosis almost always points to a clinically significant diagnosis, and investigations usually need to move on from the low-yield tests for vitam, Pract Green w Pale Yellow

Investigations

Haematology

How to Treat

+How to treat

COPD: Prevent, treat and comfort

Respiratory physician Lutz Beckert considers chronic obstructive pulmonary disease management, including the prevention of COPD, the importance of smoking cessation and pulmonary rehabilitation, and the lifesaving potential of addressing treatable traits. He also discusses the logic of inhaler therapy, moving from single therapy to dual and triple therapy when indicated, as well as other aspects of management

Wednesday 26 March 2025, 12:50 AM