Immunisation stress-related responses and anaphylaxis: What's the difference?

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VACCINES

Immunisation stress-related responses and anaphylaxis: What's the difference?

By Marleen Hart, Aimee Brass and Shelley Kininmonth
Vaccination [Image: Mat Napo on Unsplash]

The incidence of anaphylaxis following vaccination with Pfizer–BioNTech’s COVID-19 vaccine is slightly higher than that of schedule vaccines, so health professionals must be able to recognise this potentially fatal condition and differentiate it from immunisation stress-related responses

Key Points, The only true contraindication to the Pfizer–BioNTech COVID-19 vaccine is a proven history of anaphylaxis to the vaccine or its components. Health p, Pract Green w Pale Yellow
References

1. WHO. Immunization stress-related responses: A manual for program managers and health professionals to prevent, identify and respond to stress-related responses following immunization. Geneva: World Health Organization; 2019.

2. Loharikar A, Suragh TA, MacDonald NE, et al. Anxiety-related adverse events following immunization (AEFI): a systematic review of published clusters of illness. Vaccine 2018;36(2):299–305.

3. Pfizer New Zealand. DBL adrenaline injection. Medsafe data sheet. https://bit.ly/3xKISTA

4. Ministry of Health. Processes for safe Immunisation. In Immunisation Handbook 2020. Wellington: Ministry of Health; 2020.

5. Immunisation Advisory Centre. Oxygen no longer a requirement for vaccination services. Position statement; April 2020. https://tinyurl.com/5cc56nps