Strong case for the benefits of salt restriction in adults with chronic kidney disease

This review showed a strong case for the benefits of salt restriction in people with CKD. The authors found that reducing dietary salt considerably reduced blood pressure in people with CKD (mean systolic decrease of 6.91mmHg and mean diastolic decrease of 3.91mmHg). They also found consistent evidence that dietary salt restriction reduced proteinuria in people with earlier stage (non‐dialysed, non‐transplanted) CKD by 34–36%.

If such reductions were maintained long term, this may translate to clinically significant reductions in end‐stage kidney disease (ESKD) and cardiovascular events.

Reduced salt intake may increase symptomatic hypotension. Data were sparse for other types of adverse events.