Pharmacist prescribers Linda Bryant and Leanne Te Karu discuss positive polypharmacy for heart failure. Current evidence shows the intensive implementation of four medications offers the greatest benefit to most patients with heart failure, with significant reductions in cardiovascular mortality, heart failure hospitalisations and all-cause mortality
Goodfellow Gems #49
Goodfellow Gems #49
Wednesday 15 February 2017, 04:31 PM
Antibiotics – shorter courses (5 days) are better (pneumonia and cellulitis
A JAMA editorial1 comments on a trial of 5 versus 10 days of antibiotics for patients hospitalised with community-acquired pneumonia2. After 5 days of
References
1. Spellberg B. The New Antibiotic Mantra “Shorter is Better". JAMA Intern Med 2016. https://archinte.jamanetwork.com/article.aspx?articleid=2536180
2. Uranga A, España PP, Bilbao A, et al. Duration of antibiotic treatment in community-acquired pneumonia: a multicenter randomized clinical trial JAMA Internal Med 2016. http://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2536189
3. Hepburn MJ et al., Comparison of Short-Course (5 Days) and Standard (10 Days) Treatment for Uncomplicated Cellulitis. Arch Intern Med 2004. http://archinte.jamanetwork.com/article.aspx?articleid=760487