Goodfellow Gems #56

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Goodfellow Gems #56

Bruce Arroll

Wednesday 24 May 2017, 01:03 PM

Spironolactone; effective but regular serum potassium checks recommended forever

Spironolactone is effective for NYHA class III and IV heart failure and hypertension (4th or 5th line) but can be a difficult drug to use. Elevated se

Gems

References

1. KMC Verhamme et al. Spironolactone and risk of upper gastrointestinal events: population based case-control study BMJ 2006. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1539051/
2. Spironolactone—potion or poison? Drug and Therapeutics Bulletin Feb 2017. http://dtb.bmj.com/content/55/2/13

How to Treat

+How to treat

Heart failure

Pharmacist prescribers Linda Bryant and Leanne Te Karu discuss positive polypharmacy for heart failure. Current evidence shows the intensive implementation of four medications offers the greatest benefit to most patients with heart failure, with significant reductions in cardiovascular mortality, heart failure hospitalisations and all-cause mortality

Wednesday 29 January 2025, 12:45 AM