Pharmacist prescribers Linda Bryant and Leanne Te Karu discuss positive polypharmacy for heart failure. Current evidence shows the intensive implementation of four medications offers the greatest benefit to most patients with heart failure, with significant reductions in cardiovascular mortality, heart failure hospitalisations and all-cause mortality
With the right approach, irritable bowel syndrome should not be a life sentence
With the right approach, irritable bowel syndrome should not be a life sentence

Dietitian Fiona Kendall kicks off a new column on nutrition by discussing the problem of irritable bowel syndrome and its solutions
1. Lovell RM, Ford AC. Global prevalence of and risk factors for irritable bowel syndrome: a meta-analysis. Clin Gastroenterol Hepatol 2012;10(7):712–21.e4.
2. Sperber AD, Dumitrascu D, Fukudo S, et al. The global prevalence of IBS in adults remains elusive due to the heterogeneity of studies: a Rome Foundation working team literature review. Gut 2017;66(6):1075–82.
3. Levy RL, Jones KR, Whitehead WE, et al. Irritable bowel syndrome in twins: hereditary and social learning both contribute to etiology. Gastroenterol 2001;121(4):799–804.
4. Koloski NA, Jones M, Kalantar J, et al. The brain--gut pathway in functional gastrointestinal disorders is bidirectional: a 12-year prospective population-based study. Gut 2012;61(9):1284–90.
5. Peters SL, Yao CK, Philpott H, et al. Randomised clinical trial: the efficacy of gut-directed hypnotherapy is similar to that of the low FODMAP diet for the treatment of irritable bowel syndrome. Aliment Pharmacol Ther 2016;44(5):447–59.