Prostate cancer consultations are common in primary care and there is no one approach to testing and treatment that fits all patients. Urologist Simon van Rij discusses the key considerations and options for personalised care, appropriate investigation and treatment
Ivermectin for COVID? The jury is still out
Ivermectin for COVID? The jury is still out
Jim Vause trawls through the evidence of using Ivermectin to treat and prevent COVID-19 and finds “a right old mess”
[1] British Ivermectin Recommendation Development panel. The BIRD recommendation on the use of ivermectin for Covid-19. Available online @ rancesoir.fr/sites/francesoir/files/media-icons/bird-proceedings-02-03-2021-v151.pdf
[2] Bryant, Andrew MSc1,*; Lawrie, Theresa A. MBBCh, PhD2; Dowswell, Therese PhD2; Fordham, Edmund J. PhD2; Mitchell, Scott MBChB, MRCS3; Hill, Sarah R. PhD1; Tham, Tony C. MD, FRCP4 Ivermectin for Prevention and Treatment of COVID-19 Infection: A Systematic Review, Meta-analysis, and Trial Sequential Analysis to Inform Clinical Guidelines, American Journal of Therapeutics: July/August 2021 - Volume 28 - Issue 4 - p e434-e460 doi:
10.1097/MJT.0000000000001402https://journals.lww.com/americantherapeutics/Fulltext/2021/08000/Ivermectin_for_Prevention_and_Treatment_of.7.aspx
[3] Kory P, Meduri GU, Varon J, Iglesias J, Marik PE. Review of the Emerging Evidence Demonstrating the Efficacy of Ivermectin in the Prophylaxis and Treatment of COVID-19. Am J Ther. 2021 Apr 22;28(3):e299-e318. doi: 10.1097/MJT.0000000000001377. PMID: 34375047; PMCID: PMC8088823. Available online @ https://osf.io/wx3zn/
[4] Hill A, Abdulamir A, Ahmed S, Ashgar A, Babalola OE, Basri E, et al. Meta-analysis of randomized trials of ivermectin to treat SARS-CoV-2 infection. researchsquare.com/article/rs-148845/v1 (first received 19 January 2021). [DOI: 10.21203/rs.3.rs-148845/v1] https://assets.researchsquare.com/files/rs-148845/v1_stamped.pdf?c=1611086534
[5] Popp M, Stegemann M, Metzendorf M-I, Gould S, Kranke P, Meybohm P, Skoetz N, Weibel S. Ivermectin for preventing and treating COVID‐19. Cochrane Database of Systematic Reviews 2021, Issue 7. Art. No.: CD015017. DOI: 10.1002/14651858.CD015017.pub2. Accessed 31 August 2021. https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD015017.pub2/full#CD015017-sec-0134
[6] Nature. News. Flawed ivermectin preprint highlights challenges of COVID drug studies. Sarah Reardon Available online @ https://www.nature.com/articles/d41586-021-02081-w