Metformin-induced B12 deficiency: Easily overlooked but easily treated

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PHARMACOTHERAPY

Metformin-induced B12 deficiency: Easily overlooked but easily treated

By Rachel Gray
Old feet
Was the numbness in Marian’s feet caused by her diabetes or a complication of her treatment? [Image: Sabine van Erp on Pixabay]

Metformin is generally described as safe, effective and cheap, but one notable harm associated with its use is vitamin B12 deficiency

Key points, The serum level of vitamin B12 is not a particularly sensitive indicator of deficiency, and severe symptoms can occur within the normal reference rang, Pract Green w Pale Yellow
References

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