Using the right tests in the right people to improve diagnosis rate of coeliac disease

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GASTROENTEROLOGY

Using the right tests in the right people to improve diagnosis rate of coeliac disease

19 August 2020

Vanessa Weenink

Wednesday 19 August 2020, 12:30 AM

The HLA-DQ2.5 pair of alleles creates a receptor protein that binds wheat gluten very tightly, causing the T-cell to release a lot of signalling molecules, resulting in inflammation

Gastroenterologist Alan Fraser reviews issues surrounding the diagnosis of coeliac disease, as well as positive and negative aspects of the gluten-free diet

Key points, To improve the diagnosis rate of coeliac disease, there should be liberal use of tissue transglutaminase antibody testing in high-risk groups; human l, Pract Green w Pale Yellow

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