Sweet urine, bitter outcome: Empagliflozin and balanoposthitis

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Sexual health

Sweet urine, bitter outcome: Empagliflozin and balanoposthitis

By Massimo Giola
Sugar
Urine loaded with sugar offers an excellent growth medium for fungi and bacteria [Image: Mikhail Nilov on Pexels]

Sexual health specialist Massimo Giola continues his series of short, mostly clinical case-based sexual health articles. This year, he has in mind a mix of transgender medicine and sexology topics, but he starts with a genital dermatology issue he has seen a few times recently

Key points, Sodium-glucose cotransporter-2 inhibitors (dapagliflozin and empagliflozin) work by causing glycosuria. Urinary tract infections and genital fungal , Pract Green w Pale Yellow
References

1. Johnsson KM, Ptaszynska A, Schmitz B, et al. Vulvovaginitis and balanitis in patients with diabetes treated with dapagliflozin. J Diabetes Complications 2013;27(5):479–84.

2. Nyirjesy P, Sobel JD, Fung A, et al. Genital mycotic infections with canagliflozin, a sodium glucose co-transporter 2 inhibitor, in patients with type 2 diabetes mellitus: a pooled analysis of clinical studies. Curr Med Res Opin 2014;30(6):1109–19.