Pharmacist prescribers Linda Bryant and Leanne Te Karu discuss positive polypharmacy for heart failure. Current evidence shows the intensive implementation of four medications offers the greatest benefit to most patients with heart failure, with significant reductions in cardiovascular mortality, heart failure hospitalisations and all-cause mortality
Intermittent fasting: Starting small and building up can benefit many people
Intermittent fasting: Starting small and building up can benefit many people
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Dietitian Fiona Kendall reviews recent research into the benefits of intermittent fasting for healthy people and those with a variety of health issues
1. Sutton EF, Beyl R, Early KS, et al. Early time-restricted feeding improves insulin sensitivity, blood pressure, and oxidative stress even without weight loss in men with prediabetes. Cell Metab 2018;27(6):1212–21.e3.
2. Cho Y, Hong N, Kim KW, et al. The effectiveness of intermittent fasting to reduce body mass index and glucose metabolism: A systematic review and meta-analysis. J Clin Med 2019;8(10):1645.
3. Beaulieu K, Casanova N, Oustric P, et al. Matched weight loss through intermittent or continuous energy restriction does not lead to compensatory increases in appetite and eating behavior in a randomized controlled trial in women with overweight and obesity. J Nutr 2020;150(3):623–33.
4. Sadeghirad B, Motaghipisheh S, Kolahdooz F, et al. Islamic fasting and weight loss: a systematic review and meta-analysis. Public Health Nutr 2014;17(2):396–406.
5. Yeoh EC, Zainudin SB, Loh WN, et al. Fasting during Ramadan and associated changes in glycaemia, caloric intake and body composition with gender differences in Singapore. Ann Acad Med Singap 2015;44(6):202–06.
6. Furmli S, Elmasry R, Ramos M, et al. Therapeutic use of intermittent fasting for people with type 2 diabetes as an alternative to insulin. BMJ Case Rep 2018;2018:bcr2017221854.