‘Flozins’ reduce diabetes complications, but beware of euglycaemic ketoacidosis

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PHARMACOTHERAPY

‘Flozins’ reduce diabetes complications, but beware of euglycaemic ketoacidosis

3 February 2021

By Leanne Te Karu and Linda Bryant

Wednesday 3 February 2021, 12:15 AM

Consuming a diet very low in carbohydrates is a risk factor for euglycaemic ketoacidosis while taking a flozin [Image: Alex Munsell on Unsplash]

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Key points, Sodium-glucose cotransporter-2 inhibitors reduce renal, cardiovascular and heart failure complications of diabetes, while lowering blood glucose level, Pract Green w Pale Yellow

Medicines and Therapies

Endocrinology

Health Equity

References

Gomez-Peralta F, Abreu C, Lecube A, et al. Practical approach to initiating SGLT2 inhibitors in type 2 diabetes. Diabetes Ther 2017;8(5):953–62.
Musso G, Saba F, Cassader M, et al. Diabetes ketoacidosis with SGLT2 inhibitors. BMJ 2020;371:m4147.
Neuen BL, Young T, Heerspink HJL, et al. SGLT2 inhibitors for the prevention of kidney failure in patients with type 2 diabetes: a systematic review and meta-analysis. Lancet Diabetes Endocrinol 2019;7(11):845–54.
Yandrapalli S, Aronow WS. Cardiovascular benefits of the newer medications for treating type 2 diabetes mellitus. J Thorac Dis 2017;9(7):2124–34.

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