Is ChatGPT all I need to answer my pharmacotherapy questions?

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Pharmacotherapy

Is ChatGPT all I need to answer my pharmacotherapy questions?

Linda Bryant

Weight
Low-dose quetiapine is associated with weight gain, but this is not in the cardiovascular risk calculation [Image: I Yunmai on Unsplash]

Pharmacist prescriber Linda Bryant looks at two answers to the same question about quetiapine – one from a clinical pharmacist and the other from ChatGPT

Key points, Mental health conditions and antipsychotics are both associated with increased cardiovascular disease risk. There is a lack of evidence regarding me, Pract Green w Pale Yellow
References

1. Ministry of Health. Cardiovascular Disease Risk Assessment and Management for Primary Care. Wellington, NZ: Ministry of Health; 2018.

2. Wu H, Siafis S, Hamza T, et al. Antipsychotic-induced weight gain: Dose-response meta-analysis of randomized controlled trials. Schizophr Bull 2022;48(3):643–54.

3. Stogios N, Smith E, Bowden S, et al. Metabolic adverse effects of off-label use of second-generation antipsychotics in the adult population: a systematic review and meta-analysis. Neuropsychopharmacology 2022;47(3):664–72.

4. Williams SG, Alinejad NA, Williams JA, Cruess DF. Statistically significant increase in weight caused by low-dose quetiapine. Pharmacotherapy 2010;30(10):1011–15.

5. Ventriglio A, Baldessarini RJ, Vitrani G, et al. Metabolic syndrome in psychotic disorder patients treated with oral and long-acting injected antipsychotics. Front Psychiatry 2019;9:744.

6. Hardy M, Harvey H. Artificial intelligence in diagnostic imaging: impact on the radiography profession. Br J Radiol 2020;93(1108):20190840.

7. Moingeon P. Artificial intelligence-driven drug development against autoimmune diseases. Trends Pharmacol Sci 2023;44(7):411–24.